Rilax is a natural sleep supplement that improves sleep quality and promotes relaxation so that the user will get the healthy and restorative sleep his body needs.
Rilax contains two active ingredients:
- Alpha S1-Casein Tryptic Hydrolysate, a bioactive peptide extracted from the raw, pure and high quality milk of only the Holstein breed in France. Reared in family-sized farms, these cows do not experience the inhumanity of industrial livestock farming. They live in decent conditions which are compatible with animal welfare. Their natural feedstuff is derived mainly from the farm.
- L-Theanine, an amino-acid derived from green tea leaves (Camellia sinensis). Traditionally, drinking green tea is enjoyed by some Asian cultures and know to help with relaxation.
Rilax combines the relaxing properties of two safe ingredients scientifically proven to promote relaxation and restful sleep.
Because Alpha S1-Casein Tryptic Hydrolysate has a high and selective affinity for some receptors in the brain called GABA-A receptors, it stimulates the activity of Gamma-Amino Butyric Acid (GABA), a neuro-transmitter known to inhibit anxiety and the stress response in the brain. This mechanism of action therefore results in Alpha S1-Casein Tryptic Hydrolysate’s relaxing properties. It has no side-effects, is not addictive and is hypoallergenic. Unlike benzodiazepines, Alpha S1-Casein Tryptic Hydrolysate does not have any toxic effect on the body and does not create any addiction, even at a high doses. It therefore acts effectively and naturally.
The amino acid stimulates the mind to produce alpha brain waves, the sign you’re deeply relaxed, and yet allows the brain to remain mentally alert. It also aids in the creation of GABA, gamma amino butyric acid, an inhibitory neurotransmitter responsible for influencing the levels of dopamine and serotonin. L-theanine has also been shown to reduce blood pressure in an animal model of hypertension. Further, it dampens the excitatory effects of caffeine, as measured by EEG and blood pressure.
At the end of the 80’s, researchers have wondered about the origin of the calm state of babies after drinking milk. They hypothesized that a milk constituent could explain this soothing effect. Through many years of research, they succeeded in identifying a bio-peptide present in milk protein with natural relaxing properties.
No. At first, the decapeptide is not present by itself in milk and is encrypted in Alpha S1-Casein Tryptic Hydrolysate. It could be released in neonates but not in adults. The enzymatic system in adults is indeed much more complex and cannot allow the quantitative delivery of this specific sequence from the protein.
Rilax will have some positive effect on sleep from the very first time it is taken. It is effective about an hour after intake. A real sensation of well-being appears after a few days of intake. However, it will not cause drowsiness, is not a drug and therefore different people with different sleep problems will experience benefits differently.
A 2011 survey was conducted amongst users. The key findings were:
- 74% (3 out of 4) experience better sleep quality within 7 days
- 46% (1 out of 2) experience better sleep quality within 3 days
- 19% (1 out of 5) experience better sleep quality within 1 day (25% are not sure when they first experience results)
93% are satisfied with Rilax
97% would take Rilax again
98% would recommend Rilax to family members & friends
Top 3 benefits experienced are:
- Falling asleep easier and faster
- Sleeping right through or longer and waking up less frequently
- Waking up feeling slept well, refreshed and ready to face the day
Even at higher doses, Rilax has no sedative effect. People who take Rilax feel more relaxed and sleep better or fall asleep easier at bedtime. One can remain awake and attentive if there is a need to.
In studies, Rilax’s Alpha S1-Casein Tryptic Hydrolysate has shown to be physiologically effective about 1 hour after the intake. Nevertheless, a real sensation of wellbeing frequently appears after one week to 15 days. Rilax helps to promote better sleep and regulate stress and stress symptoms. The perceived effect may be different from one situation to another, depending on the individual.
We recommend that you allow for a full night’s sleep, which for most adults, is about 7-8 hours. However, Rilax should not prevent you from waking up earlier if necessary.
When your body is getting the sleep it needs, it should take about 15-20 minutes to fall asleep at night and you should be able to wake up easily in the morning.
These states need a medical check-up. Rilax is not a drug but a food supplement.
Rilax should not be compared with benzodiapines because it is a food supplement, not a drug and it is not intended to cure any anxious pathology.
If you are suffering from severe sleeping issues, we recommend seeking advice from a physician or medical professional. However, it is worthwhile to try a natural product such as Rilax. A recent clinical study published in The Open Sleep Journal (2009;2) showed that Rilax’s active ingredient, Alpha S1-Casein Tryptic Hydrolysate, helped a majority of participants to fall asleep faster, as well as significantly improve various aspects of sleep disorders. Results indicated improvement in sleep quality after two weeks of supplementation, along with decreases in sleep latency and daytime dysfunction after four weeks of supplementation.
Each person may adapt the intake, whether in the morning or in the evening, depending on his/her feelings and specific needs.
Directions for Use:
- To promote sleep: 1 capsule a day, before bedtime.
- For general relaxation and to relieve stress: 1 capsule taken during the day
- Chronic stress: 1 capsule a day, before bedtime.
- Acute stress: 2 capsules taken together, before bedtime
Rilax can be taken as needed, or every night. For people with sleep issues, you may need to take Rilax continuously for 2 weeks in order for Rilax to begin regulating your sleep quality.
Rilax may be used to help people coping with stress from daily life, without side effects (sedation, disinhibition, tolerance). For people who face high stress levels daily, taking Rilax regularly will help to regulate their stress levels and hence, help to lower the risk of stress-related disorders.
Rilax can also be taken as a daily diet to deal with a difficult and stressful period. The benefit appears after a few days. After a two-week or one-month treatment period they can continue depending on the person and its stress level. In this case, it is recommended to consume Rilax prior to bedtime. This recommendation is based on the fact that the lack of sleep, often provoked by stress of the day, increases the stress level. The relaxation provoked by Rilax helps to induce a better sleep, which prepares the person for a better following day. It can help break the vicious circle.
The normal dosage is one capsule a day, one hour before bedtime. This dosage can be increased for a person with a higher body weight than the average, or who is experiencing a situation that causes an additional level of stress.
Depending on the situation, the dosage for Rilax can be varied:
- One capsule per day, taken one hour before sleep is the minimum recommended dose for one month for general sleep issues.
- One capsule per day, taken one hour before the stressful event (facing examination, an important meeting, making a public speech, etc).
- Two capsule per day for two weeks for faster action on your emotional state during a particular stressful period (change of career, moving house, quitting smoking, etc.)
People can adopt their own way of taking Rilax. It can be taken:
- nightly for better sleep
- as and when needed for better sleep
- in a once off intake to cope with a specific immediate need (exam, important meeting…) or a few days before a stressful event to anticipate.
- as a daily diet for several days and can even be used for several weeks during difficult and stressful periods in case of chronic symptoms, depending on the person and the stress level.
Rilax’s ingredients, Alpha S1-Casein Tryptic Hydrolysate and L-Theanine both have been extensively researched.
The effectiveness of Alpha S1-Casein Tryptic Hydrolysate has been the subject of 7 rigorous clinical studies, conducted between 1999 and 2011 on 394 adult volunteers, all supervised by healthcare professionals. These studies were carried out according to the Clinical Best Practice Directive under the supervision of official ethics committees, and used biological means to confirm the positive impact of Alpha S1-Casein Tryptic Hydrolysateon the body (e.g. blood pressure and heart rate).
The trials were randomized, double-blind and placebo-controlled. Clinical studies were made according to Good Clinical Practice Guidelines with official ethical committees.
Tests which have already been validated by the scientific community, for example, Stroop test, Cold pressor test, Spielberger questionnaires, etc were used. They have not been developed specifically for studies on the ingredients.
There are substantial scientific evidence to show that Alpha S1-Casein Tryptic Hydrolysate helps to improve sleep quality as well as to decrease and modulate stress symptoms naturally.
A recent clinical study was conducted in Tokyo on 44 Japanese subjects (men and women aged 25-40) with insomnia by a team of scientists from the Sleep Centre, University Hospital of Geneva, Switzerland, the Laboratoire de NeuroSciences Comportementales, France and the Ashikaga Institute of Technology, Japan. The published study in The Open Sleep Journal (2009;2) showed that Alpha S1-Casein helped a majority of participants to fall asleep faster, as well as significantly improve various aspects of sleep disorders. Results indicated:
- Improvement in sleep quality after two weeks of supplementation.
- Decrease in sleep latency after four weeks of supplementation.
- Decrease in daytime dysfunction after four weeks of supplementation
The Proclaim study was performed on 63 stressed women (aged 18 to 61) over 30 days. Alpha S1-Casein was particularly efficient on the subjects who demonstrated the highest initial intensity of symptoms, suggesting that this milk peptide has regulating properties on stress-related disorders. Results:
- A significant greater positive evolution of stress symptoms in 5 different areas was demonstrated in the group taking Alpha S1-Casein vs placebo.
The Necker Hospital study was conducted in Paris among 42 male volunteers (aged 18 to 35) facing acute stress over 2 days. Results:
- During the stroop test, SBP and DBP responses were signicantly reduced in the alpha S1-casein group compared to the placebo group.
- After the stress test, blood cortisol level had remained stable in the placebo group while it has decreased significantly in the alpha S1-casein group.
The CRSSA study was conducted over 30 days with the recommended dose of 150 mg/day of Lactium® on 52 volunteers in perfect health (25 men and 27 women aged 18 to 40, selected at random). The results following the Stroop test showed:
- a reduction in blood pressure for the group which used Lactium®, the physiological response to stress being an increase in blood pressure.
The study performed at a Military Base in Quebec in 2004 tested the effect of Alpha S1-Casein on ten national and international biathletes who were subjected to 4 weeks of rigorous training. Results showed:
- The mean cortisol (stress hormone) level was significantly lower in the athletes taking Alpha S1-Casein, while it was higher in athletes taking placebo, at week 4 compared to the basal level observed during the first week.
- Alpha S1-Casein can help counter the negative physiological effects caused by the rise of cortisol levels induced by rigorous training and may therefore ensure performance development.
The general picture that emerges from L-theanine research is an anti-stress effect, with the strongest hypothesis being that anti-glutamate receptor activity is the primary driver of this effect.
L-theanine supplementation has been shown to increase brain α-waves (8-10 Hz range) which are associated with reduced stress and anxiety. Beyond relaxation, increased α-waves are associated with selective attention mechanisms and mental alertness. These altered wave functions are said to be evidence that L-theanine has ‘relaxing and attention promoting’ properties. There’s also literature that report increased theta wave function which is associated with learning and memory.
Some preliminary human studies, typically using doses of L-theanine about 10 to 20 times higher than that in a cup of tea, have suggested possible benefits, such as the following:
In a Japanese study in the Journal of Physiological Anthropology, college students who took L-theanine experienced less anxiety and had smaller increases in blood pressure when under psychological or physical stress than when they took a placebo.
Similarly, another Japanese study in Pharmacology, Biochemistry, and Behavior found that graduate students who took L-theanine experienced less anxiety (as measured by a questionnaire and by a salivary marker for stress) when they were assigned stressful work in a pharmacy, compared to a placebo.
In a Canadian study in Alternative Medicine Review, L-theanine improved some aspects of sleep quality in boys with attention-deficit hyperactivity disorder (ADHD).
Study 4: L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
In a preliminary Israeli study in the Journal of Clinical Psychiatry, L-theanine helped relieve anxiety symptoms and augment antipsychotic treatment in patients (ages 19 to 55) with schizophrenia.
Stressful condition increased the level of sAA that was essentially affected by individual trait anxiety. The low levels of pre-practice sAA and subjective stress in the L-theanine-group suggest that L-theanine intake suppressed initial stress response of students assigned for a long-term commitment of pharmacy practice.
Both Rilax’s ingredients, Alpha S1-Casein Tryptic Hydrolysate and L-theanine are both classified as GRAS (generally regarded as safe) by the FDA.
No, Rilax provides a safe way to get a restful night’s sleep without worrying about addiction or after-effects.
Rilax does not have any negative side after-effects, such as grogginess, headaches or lack of mental clarity following a night’s rest. It is formulated to promote relaxation and better sleep.
In particular, Alpha S1-Casein Tryptic Hydrolysate does not induce addiction, tolerance, memory loss, disinhibition nor sedation. It does not cause arousal, reactivity or alertness decrease.
Furthermore, no physiological adverse effects were noticed. In particular, neither weight gain nor modification of the ambulatory blood pressure was observed
Alpha S1-Casein Tryptic Hydrolysate modulates blood pressure increase during a stressing situation but not the ambulatory blood pressure (hypertension). Thus, it does not have an anti-hypertensive or hypotensive effect.