Rilax’s ingredients, Alpha S1-Casein Tryptic Hydrolysate and L-Theanine both have been extensively researched.
The effectiveness of Alpha S1-Casein Tryptic Hydrolysate has been the subject of 7 rigorous clinical studies, conducted between 1999 and 2011 on 394 adult volunteers, all supervised by healthcare professionals. These studies were carried out according to the Clinical Best Practice Directive under the supervision of official ethics committees, and used biological means to confirm the positive impact of Alpha S1-Casein Tryptic Hydrolysateon the body (e.g. blood pressure and heart rate).
The trials were randomized, double-blind and placebo-controlled. Clinical studies were made according to Good Clinical Practice Guidelines with official ethical committees.
Tests which have already been validated by the scientific community, for example, Stroop test, Cold pressor test, Spielberger questionnaires, etc were used. They have not been developed specifically for studies on the ingredients.
There are substantial scientific evidence to show that Alpha S1-Casein Tryptic Hydrolysate helps to improve sleep quality as well as to decrease and modulate stress symptoms naturally. Study 1: Effects of a Bovine Alpha S1-Casein Tryptic Hydrolysate (CTH) on Sleep Disorder in Japanese General Population A recent clinical study was conducted in Tokyo on 44 Japanese subjects (men and women aged 25-40) with insomnia by a team of scientists from the Sleep Centre, University Hospital of Geneva, Switzerland, the Laboratoire de NeuroSciences Comportementales, France and the Ashikaga Institute of Technology, Japan. The published study in The Open Sleep Journal (2009;2) showed that Alpha S1-Casein helped a majority of participants to fall asleep faster, as well as significantly improve various aspects of sleep disorders. Results indicated: Improvement in sleep quality after [...]
The general picture that emerges from L-theanine research is an anti-stress effect, with the strongest hypothesis being that anti-glutamate receptor activity is the primary driver of this effect. L-theanine supplementation has been shown to increase brain α-waves (8-10 Hz range) which are associated with reduced stress and anxiety. Beyond relaxation, increased α-waves are associated with selective attention mechanisms and mental alertness. These altered wave functions are said to be evidence that L-theanine has 'relaxing and attention promoting' properties. There's also literature that report increased theta wave function which is associated with learning and memory. Some preliminary human studies, typically using doses of L-theanine about 10 to 20 times higher than that in a cup of tea, have suggested possible benefits, such as the following: Study 1: Effects of L-theanine or [...]